Latest News : Coronavirus Update: Coronavirus Latest Research Updates by Prof. Dr. Muhammad Mukhtar. Admissions: SKILLS EDUCATION OPPORTUNITIES (OPENING ITS DOORS IN SPRING 2021) BIOSAFETY SKILLS @ WORKPLACES Being offered in collaboration with National Vocational and Technical Training Commission (NAVTTC) and higher education institutions across the world

PUBLICATIONS


Peer- reviewed Research Papers

  • Aslam A, Shahzad MI, Parveen S, Ashraf H, Naz N, Zehra SS, Kamran Z, Qayyum A and Mukhtar M, 2016. Evaluation of antiviral potential of different Cholistani plants against infectious bursal disease and infectious bronchitis virus. Pak Vet J, 36(3): 302-306.
  • Mukhtar M, Griffin LD. (2015) Bioremediation – A beneficial use of biotechnology and allied engineering technologies in oil producing regions. Int J of Sustainable Water & Environmental Systems, 7(2):83-85.
  • Mukhtar M, (2015) Bacterial and viral infections impact on human health [EDITORIAL]. EC Bacteriology and Virology Res, 1.1:1-4.
  • Murtaza G,Mukhtar M, and Sarfaraz A (2015) A Review: Antifungal potentials of medicinal plants. J Bioresource Management, 2(2):23 - 31.
  • Rasool KG, Khan MA, Aldawood AS, Tufail M, Mukhtar M, and Takeda M. (2015) Identification of proteins modulated in the date palm stem infested with red palm weevil (Rhynchophorus ferrugineus Oliv.) using two dimensional differential gel electrophoresis and mass spectrometry. Intn J Mol Sci 16: 19326-19346.
  • Malik S, Ahmad S, Sadiq A, Alam K, Wariss H, Ahmad I, Hayat M, Anjum S, and Mukhtar M, (2015) A comparative ethnobotanical study of Cholistan (an arid area) and Pothwar (a semi-arid area) of Pakistan for traditional medicines. Journal of Ethnobiol and Ethnomed, 11:31.
  • Rasool KG, Khan MA, Aldawood AS, Tufail M, Mukhtar M, and Takeda M. (2014) Optimization of protein isolation from date palm plants and its utilization in differential proteomics associated with red palm weevil infestation. Pak J Agric Sci. 51(4): 907-917.
  • Shamim T, Ahmad M and Mukhtar M. (2014) Antihyperglycemic and hypolipidemic effects of methanolic extract of Euphorbia prostrata on alloxan-induced diabetic rabbits. Eur Sci J. August 2014, Special Edition, p. 458 - 465.
  • Ahmad S, Wariss HM, Alam K, Anjum S, and Mukhtar M. (2014) Ethnobotanical studies of plant resources of Cholistan Desert, Pakistan. Intn J Sci and Res. 3(6): 1782 - 1788.
  • Wariss HM, Mukhtar M, Anjum S, Bhatti GR, Pirzada SA, and Alam K. (2013) Floristic composition of the plants of the Cholistan Desert, Pakistan. Amer J Plant Sci 4:58 - 65.
  • Mukhtar M, Rasool KG, Parrella MP, Sheikh QI, Pain A, Lopez-Llorca LV, Aldryhim YN, Mankin RW and Aldawood AS. (2011) New Initiatives for Management of Red Palm Weevil Threats to Historical Arabian Date Palms. Florida Entomologist, 94(4):733-736.
  • Saqib MAN, Fatima M, Awan IN, Shahzad MI, Rizvi SKA, Mukhtar M, and Khanum A. (2011) Optimized conditions for high-level solubilization and purification of recombinant camel growth hormone in Escherichia coli. Afr J Biotechnol 10(61):13284- 13291
  • Parveen Z, Mukhtar M, Pomerantz RJ. (2010) Generation of retroviral particles for the spleen necrosis virus (SNV)-based vector system and their use in transduction of various cell types. Cold Spring Harb Protoc. 2010 Jun; 2010(6):pdb.prot5435
  • Acheampong EA, Roschel C, Mukhtar M, Srinivasan A, Rafi M, Pomerantz RJ, Parveen Z. (2009) Combined effects of hyperglycemic conditions and HIV-1 Nef: a potential model for induced HIV neuropathogenesis. Virology J 6:183 doi: 10.1186/1743-422X-6- 183.
  • Arshad M, Hussain I, Ashraf MY, Noureeen S, and Mukhtar M. (2009) Study on agromorphological variation in germplasm of Lasiurus scindicus from Cholistan Desert, Pakistan. Pak J Bot 41:1331-1337.
  • Ahmad T, Sohail K, Rizwan M, Mukhtar M, Bilal R, and Khanum A. (2009) Prevalence of Helicobacter pylori pathogenicity-associated cagA and vacA genotypes among Pakistani dyspeptic patients. FEMS Immunol Med Microbiol 55(1):34-38.
  • Shahzad MI, Khawaja KN, Mukhtar M, Khanum A. (2008) Passive immunization against highly pathogenic avian Influenza Virus (AIV) strain H7N3 with antiserum generated from viral polypeptides protect poultry birds from lethal viral infection. Virol J 5(1):144 [MANUSCRIPT FEATURED ON BIOMED CENTRAL AND HONORED WITH HIGLY ACCESSED SEAL]
  • Owe-Young R, Webster NL, Mukhtar M, Pomerantz RJ, Smythe G, Walker D, Armati PJ, Crowe SM and Brew BJ. (2008) Kynurenine pathway metabolism in human blood-brainbarrier cells: implications for immune tolerance & neurotoxicity. J. Neurochem 105(4):1346 – 1357.
  • Mukhtar M, Arshad M, Ahmad M, Wigdahl B, and Parveen Z. (2008) Antiviral potentials of medicinal plants. Virus Research, 131, 111-120.
  • Argyris EG, Acheampong E, Wang F, Huang J, Chen K, Mukhtar M, and Zhang H. (2007) The interferon (IFN)-induced expression of APOBEC3G in human blood-brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to the central nervous system. Virology 367:440-451.
  • Parveen, Z, Acheampong E, Pomerantz RJ, Jacobson J, Wigdahl B, and Mukhtar M. (2007) Effects of highly active antiretroviral therapy on HIV-1-associated oral complications. Current HIV Research 5:281-292.
  • Cheng X, Mukhtar M, Acheampong E, Srinivasan A, Rafi M, Pomerantz RJ, and Parveen Z. (2007) HIV-1 Vpr potently induces programmed cell death in the CNS in vivo. DNA Cell Biology 26:116-131.
  • Acheampong E, Parveen Z, Mengistu A, Ngoubilly N, Wigdahl B, Lossinsky, AS, Pomerantz RJ, and Mukhtar M. (2007) The cholesterol depleting drugs Statin protect post-mitotically differentiated human neurons against ethanol and HIV-1-induced oxidative stress in vitro. J Virol. 81:1492-501.
  • Barodka VM, Acheampong E, Powell G, Lobach L, Logan DA, Parveen Z, Armstead V, and Mukhtar M.(2006) Antimicrobial Effects of Liquid Anesthetic Isoflurane on Candida albicans Journal of Trans Med, Nov 9;4:46.
  • Lossinsky AS, Jong A, Fiala M, Mukhtar M., Buttle KF, and Marylou Ingram M. (2006) The histopathology of Candida albicans invasion in neonatal rat tissues and in the human blood-brain barrier in culture revealed by light, scanning, transmission and immunoelectron microscopy. Histol Histopathol. 21(10): 1029-41.
  • Mukhtar M. (2005) Evolution of Biomarkers: Drug Discovery to Personalized Medicine, Drug Discovery Today, 10(18): 1216-1218.
  • Mukhtar M, Acheampong E, Parveen Z, and Pomerantz RJ. (2005) T-cells and excitotoxicity - HIV-1 and other neurodegenerative disorders. NeruoMolecular Medicine, 7: 265-273.
  • Nunnari G, Xu Y, Acheampong EA, Fang J, Daniel R, Zhang C, Zhang H, Mukhtar M, and Pomerantz RJ. (2005) Exogenous IL-7 induces Fas-mediated human neuronal apoptosis: Potential effects during HIV-1 infection. J Neurovirology, 11(4): 319-28.
  • Acheampong E, Parveen Z, Wasmuth-Peroud V, Kalayeh M, Bashir A, Diecidue R, Mukhtar M, and Pomerantz RJ. (2005) Molecular interactions of HIV-1 with primary human oral keratinocytes. J Virol. 79:8440-53.
  • Mukhtar M. (2005) Human immunodeficiency virus type 1 (HIV-1) neuropathogenesis in in vitro models. J Cell Tissue Res. 5(2):507-12.
  • Fang, J, Acheampong E, Dave R, Wang F, Mukhtar M, and Pomerantz RJ. (2005) The RNA helicase DDX1 is involved in restricted HIV-1 Rev function in human astrocytes. Virology, 336(2): 299-307.
  • Fang, J, Acheampong E, Dave R, Wang F, Mukhtar M, and Pomerantz RJ. (2005) The RNA helicase DDX1 is involved in restricted HIV-1 Rev function in human astrocytes. Virology, 336(2): 299-307.
  • Mukhtar M, Acheampong E, BouHamdan M, and Pomerantz RJ. (2005) Downregulation of the CXCR4 co-receptor by an intracellular single chain variable fragment inhibit viral entry into primary human brain microvascular endothelial cells and post-mitotic neurons. Mol. Brain Res. 135:48-57.
  • Acheampong E, Parveen Z, Muthoga LW, Kalayeh M, Mukhtar M, and Pomerantz RJ. (2005) HIV-1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells (MVEC) via the activation of caspases. J Virol 79:4257-4269.
  • Chen W, Tang Z, Fortina P, Patel P, Addya S, Surrey S, Acheampong E, Mukhtar M, and Pomerantz RJ. (2005) Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways. Virology 334:59- 73.
  • Marusich EI, Parveen Z, Strayer D, Dornburg R, Mukhtar M, and Pomerantz RJ. (2005) Spleen Necrosis Virus (SNV)-based vector delivery of anti-HIV-1 genes potently protects human hematopoietic cells from HIV-1 infection. Virology 332:258-271.
  • Argyris, E, Kulkosky J, Meyer ME, Xu Y, Mukhtar M, Pomerantz RJ, Williams KJ. (2004) The perlecan heparan sulfate proteoglycan mediates cellular uptake of HIV-1 Tat through a pathway responsible for biological activity. Virology 330:481-6.
  • Zhou N, Fang J, Mukhtar M, Acheampong E, and Pomerantz RJ. (2004) Inhibition of HIV-1 fusion and infection with small interfering RNAs (siRNAs) targeting the chemokine co-receptor, CXCR4. Gen Ther. 11(23): 1703-12.
  • Parveen Z, Mukhtar M, Goodrich A, Acheampong E, Dornburg R, and Pomerantz RJ. (2004) Cross-packaging of human immunodeficiency virus type 1 vector RNA by spleen necrosis virus proteins – construction of a new generation of spleen necrosis virusderived retroviral vectors. J Virol 78:6480-6488.
  • Argyris EG, Acheampong E, Mukhtar M, Williams KJ, and Pomerantz RJ. (2003) Human immunodeficiency virus type 1 enters primary human brain microvascular endothelial cells by a mechanism involving cell surface proteoglycans independent of lipid rafts. J Virol 77:12140-12151.
  • Parveen Z, Mukhtar M, Rafi M, Wenger DA, Dietzschold B, Schnell M, Pomerantz RJ, and Dornburg R. (2003) Cell-type-specific gene delivery into neuronal cells in vitro and in vivo. Virology 314:74-83.
  • Fan X, Zhou N, Zhang X, Mukhtar M, Lu Z, Fang J, DuBois GC, and Pomerantz RJ. (2003) Structural and functional study of the Apelin-13 peptide, an endogenous ligand of the HIV-1 co-receptor, APJ. Biochemistry 42(34): 10163-10168.
  • Zhou N, Fang J, Acheampong E, Mukhtar M, Pomerantz RJ. (2003) Binding of ALX40- 4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1. Virol 312(1): 196 -203.
  • Zhou N, Fan X, Mukhtar M, Fang J, Patel CA, DuBois GC, and Pomerantz RJ. (2003) CellCell Fusion and Internalization of the CNS-Based, HIV-1 Co-Receptor, APJ. Virology 307(1): 22-36.
  • Acheampong E, Mukhtar M, Parveen Z, Ngoubilly N, Ahmad N, Patel C, and Pomerantz RJ. (2002) Ethanol strongly potentiates apoptosis induced by HIV-1 proteins in primary human brain microvascular endothelial cells. Virology 304(2): 222-34.
  • Mukhtar M, Harley S, Chen P, BouHamdan M, Patel C, Acheampong E, and Pomerantz RJ. (2002) Primary isolated human brain microvascular endothelial cells express diverse HIV/SIV-associated chemokine co-receptors and DC-SIGN/L-SIGN. Virology 297:78-88.
  • Patel C, Mukhtar M, Harley S, Kulkosky J, and Pomerantz RJ. (2002) Lentiviral expression of HIV-1 Vpr induces apoptosis in human neurons. J. Neurovirol 8(2): 86-99.
  • Mukhtar M, Parveen Z, and Pomerantz RJ. (2001) AIDS Vaccine 2001. Advances in AIDS research. IDrugs. 4:10(1144-1146).
  • Mukhtar M, and Pomerantz RJ. (2001) Retroviruses and opportunistic infections - Eighth Annual Conference. IDrugs 2001, 4:5 (515-517).
  • BouHamdan M, Strayer DS, Wei D, Mukhtar M, Duan L, Hoxie J, and Pomerantz RJ. (2001) Inhibition of HIV-1-infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4. Gene Ther 8: 408-418.
  • Mukhtar M, and Pomerantz RJ. (2000) Development of an in vitro blood: brain barrier model to study molecular neuropathogenesis and neurovirological disorders induced by HIV-1 infection. J Hum Virol 3(2): 324-334.
  • Patel C, Mukhtar M, and Pomerantz RJ. (2000). Human Immunodeficiency Virus Type 1 Vpr induces apoptosis in human neuronal cell. J Virol 74:9717-9726.
  • Mukhtar M, Duke H, BouHamdan M, and Pomerantz RJ. (2000) Anti-Human Immunodeficiency Virus Type 1 gene therapy in human Central Nervous System-Based Cells: An initial approach against a potential viral reservoir. Hum. Gene Ther. 11: 347-359.
  • Mukhtar M, Parveen Z, and Pomerantz RJ. (2000) Technology Evaluation: PRO-542, Progenics Pharmaceuticals Inc. Curr Opin Mol Ther 2(6): 697-702 [An evaluation review on PRO-542, an rCD4-IgG2, and its potential as an anti-HIV-1 agent].
  • Shaheen F, Sison AV, McIntosh L, Mukhtar M, and Pomerantz RJ. (1999) Analysis of HIV-1 in the cervicovaginal secretions and blood of pregnant and nonpregnant women. J. Hum. Virol. 2(3): 154-166.
  • Mukhtar M, Pomerantz RJ. (1998) How does HIV-1 cross the Blood-Brain Barrier? NeuroAids 2(1), June 1998. Published on the NeuroAIDS web site launched by Science: (American Association for the Advancement of Sciences) http://aidscience.org/neuroaids/articles/Neuro1(2).asp
  • Mukhtar M. (1998) Neuroscience of HIV infection - Eighth International Meeting. Basic research and clinical frontiers. IDrugs. 1(3):292-293.
  • Mukhtar M, Parveen Z, and Logan DA. (1996) Isolation of RNA from the filamentous fungus Mucor circinelloides. J. Microbiol Methods. 33:115-118.
  • Mukhtar M, Duan L, Bagasra O, and Pomerantz RJ. (1996) Evaluation of relative promoter strengths of the HIV-1-LTR and a chimeric RSV-LTR in T-lymphocytic cells and peripheral blood mononuclear cells: Promoters for anti-HIV-1 gene therapies. Gene Therapy, 3(8): 725-730.
  • Nikura M, Dornadula G., Zhang H, Mukhtar M, Khalili K, Bagasra O, and Pomerantz RJ. (1996) Mechanisms of transcriptional transactivation and restriction of Human Immunodeficiency Virus Type 1 replication in an astrocytic glial cell. Oncogene, 13: 313- 322.
  • Mukhtar M, Käufer NF, and Logan DA. (1996) Cloning and sequence analysis of a putative transcription factor (MTF-1) gene from Mucor circinelloides. “Biochem and Mol. Biol. Intn. 38(4): 791-799.
  • Pourrezaei K, Shvets I, DeLaurentis M, Boxman RL, Beard RB, Croitoriu N, Mukhtar M, Logan DA, and Rastogi R. (1994) Development of antimicrobial and antithrombogenic coatings for inside and outside of medical catheters. Surface and Coatings Technol. 68.69: 669-67.
  • Mukhtar M, Logan DA, and Käufer NF. (1994) A procedure to construct partial genomic libraries for gene cloning from fungi. BioTechniques 17(4): 640-642.
  • Mukhtar M, Logan DA, and Käufer NF. (1992) The Carboxypeptidase Y-encoding gene from Candida albicans and its transcription from yeast-to-hyphae conversion. Gene. 121: 173-177.
  • Mukhtar M, and Khan KM. (1988) Present status of nitrates and nitrites in vegetables. Pakistan J. Agric. Sci. 25(4): 314-317.
  • Zaman K, Mukhtar M, Siddique H, and Miszta H. (1992) The effect of aluminum on the stromal cells (in vitro) bone marrow in rats. Toxicol & Indust. Health. 8(1-2): 103-109. 66. Iqbal N, Mukhtar M, and Khan KM. (1987) Studies on enzymes activity in normal and saline soils. Pakistan J. Agric. Sci. 24 (3): 157-161.
  • Yaqub M, Mukhtar M, and Sheri AN. May 16, (1985) “Human Environment Control”. Viewpoint, X (41): 26-27.
  • Yaqub M, and Mukhtar M. (1985) Role of trace element in the growth process of fish life cycle. Pakistan Agric. VII (10): 56-57.
  • Mukhtar M, and Khan KM. (1982) Effects of salinity on soil catalase, phosphatase and urease transformation of plants residue in soil. Pakistan J. Agric. Sci. 19 (3-4): 79-85.
  • Books/Book Chapters

  • Mukhtar M. (2015) Hayat Zauq-e- Safar Kay Siwa Kuch Aur Nahen (Urdu), The Islamia University of Bahawalpur
  • Mukhtar M. (2017) The making of a best national university. Iqra Educational Network.
  • Parveen Z, Acheampong E, Pomerantz RJ, and Mukhtar M. (2009) Neurovirological Aspects of HIV Infection in the HAART Era, In “The Spectrum of Neuro-AIDS Disorders: Pathophysiology, Diagnosis, and Treatment” [ISBN No. 1555813690] p. 123-135, Edt. By Goodkin, K. et al. ASM Press.
  • Parveen Z, Mukhtar M, and Pomerantz R. (2007) Spleen Necrosis Virus-Based Vectors, In “Gene Transfer: Delivery and Expression of DNA and RNA – A Laboratory Manual” [ISBN No. 9780879697655] p. 83 – 90, Edt. By: Friedmann, T. and Rossi, J., Cold Spring Harbor Laboratory Press.
  • Acheampong E, Mukhtar M, and Pomerantz R. (2005) Alcohol and HIV-1 Neuropathogenesis In “The Neurology of AIDS” 2nd Edition. [ISBN No. 0198526105] p. 541 – 551, Edt. By: Gendelman et al. Oxford University, Press, United Kingdom & Europe.
  • Mukhtar M, Dornburg R, and Pomerantz R. (2004) Gene Therapy and HIV-1 Infection In: “Gene and Cell Therapy: Therapeutic Mechanisms and Strategies” pp. 641- 656. Edt. By Templeton, N. Publishers, Marcel, Dekker, Inc. New York.
  • Bagasra O, Amjad M, and Mukhtar M. (1999) Liposomes in Gene Therapy. In “Gene Therapy: Principles and Applications” pp. 61- 71. Edt. By Thomas Balnkenstein. Birkhäuser Verlag, Berlin.
  • Mukhtar M, and Bagasra O. (1997) Computer Assisted Designing of Primers and Probes. In “In situ PCR Techniques, pp.109-118.”By Bagasra, O. Publishers, John Wiley and Sons.
  • Mukhtar M, Parveen Z, and Bagasra O. (1997) Human Gene Therapy: Dreams to realization. In “Methods in Molecular Biology, Vol. 63, pp. 415-437 Recombinant Protein Protocols: Detection and Isolation. Edt. Rocky S Tuan, Humana Press, Totowa, New Jersey.
  • Bagasra O, Mukhtar M, Shaheen F, and Pomerantz RJ. (1997) In situ PCR “Methods in Molecular Biology, Vol. 63, pp. 275-303. Recombinant Protein Protocols: Detection and Isolation. Edt. Rocky S Tuan, Humana Press, Totowa, New Jersey.